Cohort study of nearly 80,000 participants reveals the economic impact of early-stage CKD on health care utilization.
A new study conducted in Japan involving 79,988 participants sheds light on the substantial health care spending associated with early-stage chronic kidney disease (CKD). The research, utilizing nationwide health checkup and medical claims data, indicates a strong correlation between mild reductions in estimated glomerular filtration rates (eGFR), proteinuria, and health care spending over a 5-year period.
Key Findings:
- Excess Health Care Spending: The study, conducted from April 2021 to October 2023, reveals that early-stage CKD is linked to greater excess health care spending. Participants with mildly reduced eGFR, proteinuria, or a combination of both consistently exhibited higher health care spending over the examined 5-year period.
- Association Beyond Traditional Risk Factors: Even after adjusting for common risk factors such as hypertension and diabetes, mild reductions in eGFR and the presence of proteinuria were independently associated with excess health care spending.
- Longitudinal Impact: The research not only assessed the cross-sectional impact but also examined the longitudinal effects over 5 years. The findings suggest a constant need for excess health care spending in individuals with early-stage CKD, with the combination of proteinuria and mildly reduced eGFR showing an increasing trend over time.
- Preventive Measures Urged: The study concludes by emphasizing the importance of designing actions to prevent the occurrence and progression of CKD. It suggests that interventions aimed at reducing the economic burden associated with early-stage CKD are crucial for sustaining a healthcare system.
Background:
Chronic kidney disease affects a significant portion of the global population and is a known risk factor for end-stage kidney disease and cardiovascular disease. The study emphasizes that while advanced-stage CKD has been linked to higher health care utilization, evidence regarding the economic burden of early-stage CKD has been limited.
Implications:
The study’s findings highlight the need for targeted interventions and preventive measures to address early-stage CKD, considering its impact on health care spending. Identifying and addressing CKD-related practices could help reduce excess health care utilization and contribute to a more sustainable healthcare system.
Note: The information presented is based on the provided study results and abstract.